News | May 3, 2005

Feeder Selection For Pharmaceutical Extrusion Applications

Downloads:
Application Note: Feeder Selection For Pharmaceutical Extrusion Applications

The pharmaceutical industry continues to implement continuous production techniques, including hot melt extrusion, to realize the benefits of:

  • increased production rates,
  • lower production costs,
  • process efficiency, processing without the use of water or solvents (no drying),
  • and possibilities for product recycling.

Hot melt extrusion is presently one of the most widely applied techniques in the plastics industry. Currently more than half of all plastic products, including plastic bags, sheets and pipes, are manufactured by this process.

The largest potential in the pharmaceutical industry resides with the processing of active or excipient materials to produce products such as:

  • thermal binders/ sustained release tablets,
  • medical grade film products/ transdermal drug delivery systems,
  • catheter tubing, granule preparation/ immediate release dosage forms,
  • and hot melt mixed solid dosage forms.

Due to the tight tolerances demanded by the industry in general and the need for process integrity, the loss-inweight feeder must be considered as an upstream device to ensure consistent mass flow of material(s) into the inlet throat of the extruder.

Downloads:
Application Note: Feeder Selection For Pharmaceutical Extrusion Applications

Source: Coperion K-Tron